Contraindications to the use of drugs: hypersensitivity to gonadotropins, or any of the ingredients, ovarian carcinoma, uterine or mammary glands are active, untreated tumor of the hypothalamus and pituitary, increase or ovarian cysts that are not a consequence of c-m polycystic ovarian gynecological bleeding of unclear origin, pregnancy and lactation. The main pharmaco-therapeutic action: the hormone progestin. Contraindications to the use of drugs: ovarian, breast, uterus, testes, pituitary or hypothalamus, pregnancy, lactation, vaginal bleeding of unknown etiology; hypersensitivity to any component of the drug, primary ovarian failure, ovarian cysts or ovarian increase, not associated with c-IOM polycystic ovarian violation genital anatomy is incompatible with pregnancy; fibroma of raveling uterus incompatible with pregnancy, primary testicular failure. 25 mg, 50 mg, 100 mg. Side effects and complications in raveling use of drugs: minor and moderate local reactions (hematoma, pain, redness, itching or swelling); reporting system to enter the AR lutropin alfa no c-m ovarian hyperstimulation occurred less than 6% of patients, about cases with severe ovarian hyperstimulation-m were reported, with human menopausal gonadotropin here may be related to thromboembolic phenomena, ovarian twisting (complications caused by the increase of ovary) and hemoperitoneum, ectopic pregnancy, especially in women with a previous history of disease pipes, headache, Fetal Heart Rate nausea, abdominal pain, pain in the pelvic area, reproductive violation - C ovarian hyperstimulation, ovarian cysts, breast pain. Dosing and Administration of drugs: there are many individual differences in ovarian response to the introduction of gonadotropins; dose picked individually, depending on the Propylthioluracil of raveling ovaries, for the conduct of U.S. transmitting aspiration eggs. The main pharmaco-therapeutic effects: anti-estrogenic effect, a mechanism which explains the ability to specifically bind to estrogen receptors in the hypothalamus and ovaries, in small doses, the drug increases the secretion of gonadotrophic hormones (prolactin, follicle stimulating and progestin) and stimulates ovulation, in large doses, the drug inhibits the secretion of gonadotropins; shows no gestagen and androgen activity. Side effects and complications by the drug: headache, dizziness, nausea, sometimes vomiting, depression, fatigue, anxiety, insomnia, increased body weight, abdominal pain, hot flashes, blurred vision, enlargement of ovaries (ovaries may even increase to raveling - 8 cm, so you need here follow the basal t ° in the case of two-phase t ° is necessary to stop treatment) in the long introduction of the drug possible hair loss, rash with itching, allergic dermatitis, chest pain, painful menstruation, urination violations, increasing the likelihood of multiple pregnancy. The main pharmaco-therapeutic action: the follicle. Dosing and Administration of drugs: with regular raveling bleeding is recommended to begin treatment on Day 5 of the cycle: Figure I - daily dose of 50 mg daily for 5 days, under the control of ovarian response by clinical and laboratory research, ovulation usually occurs between 11 - m and 15 m day Over-the-counter Drug scheme II is used in case of failure in the treatment scheme I - daily doses of 100 mg should be taken within 5 days, starting on 5 th day of next cycle if the treatment did not lead to ovulation, can be re- course (100 mg) in the absence of ovulation and in this case, after 3-month break, raveling can try to hold another three-cycle course of treatment if after ovulation has not occurred, repeat treatment is not recommended, the total dose during the cycle should not exceed 750 mg in the absence of menstruation after use of contraceptives is advised to take 50 mg / day for 5 days. Pharmacotherapeutic group: raveling - sex hormones, and tools to influence the sexual sphere raveling .
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